Annualized spontaneous bleeding rate (AsBR) describes the number of spontaneous bleeds, or bleeds that occur without an obvious cause, over a year
Annualized bleeding rate (ABR) describes the number of bleeds that occur over a year due to any cause
*AsBR in clinical trials (interquartile range [IQR]=0–2.4 for patients ≥12 years; 0–2.2 for patients <12 years). †ABR in clinical trials (IQR = 0–4.2 for patients ≥12 years; 0–7.2 for patients <12 years).
The majority of bleeds were successfully resolved with 1 infusion.
With AFSTYLA, surgical bleeding control was rated "excellent" in 15 surgeries and "good" in 1 surgery.